Peptide Technology

Jiuzhou Pharma's peptide platform provides one-stop services from custom peptide manufacturing to registration, filing, and GMP production of peptide drug ingredients.

Jiuzhou Pharmaceutical offers high-quality peptide CDMO services, specializing in providing comprehensive & customized peptide product solutions for pharmaceutical companies, research institutions, and biotechnology companies. From small-scale R&D to large-scale production, our advanced technology platforms and experienced teams ensure that every batch of peptide products adheres to stringent quality standards.

We demonstrate strong capabilities in peptide synthesis, utilizing techniques such as solid phase, solution phase, hybrid phase, tag-assisted peptide synthesis, and original non-classical solid phase synthesis. By leveraging our expertise in small molecule synthesis, we can customize special starting materials and ensure punctual delivery of high-quality finished products. Our peptide technologies include backbone modification (some or all special amino acids), cyclization (disulfide bonds, multiple disulfide bonds, amide bonds), amidation, side chain modification (fatty acids, PEG, etc.), methylation, and fluorescent labeling. We are also capable of R&D and GMP production of high-potency products.

From complex peptide synthesis to efficient purification processes, we offer flexible production solutions tailored to your needs. Furthermore, our technical team offers comprehensive support in formulation optimization, analytical testing, and regulatory submissions for peptide drugs, ensuring the smooth progress of your projects.

Applications

●   Synthesis of protein fragments up to 78 amino acids using a hybrid phase approach.

●  Directed cyclization of a 40-amino acid peptide that contains three disulfide bonds through directed synthesis.

●  Directed modification or labeling of naked peptides through click chemistry and addition reactions for, for example, a customer's ADC and PDC drugs.

●  Our proprietary, non-classical solid phase synthesis technique has addressed issues on excess resin loading and low atomic efficiency in solid-phase synthesis and helped reduce material costs in thymopentin and eptifibatide projects.

Equipment