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Small Molecule CDMO Services
Jiuzhou Pharma provides customers worldwide with quality one-stop CDMO services throughout the entire industry chain, from preclinical chemical manufacturing and control (CMC) through phase I/II/III clinical trials and new drug applications (NDA) to global marketing.
At the end of 2023, Jiuzhou established a brand-new Animal Health unit, aim to provide efficient CDMO service for Animal health enterprise in global. Before that, Jiuzhou had already cooperated with Animal Health MNC for more than a decade.
Efficient, professional, international R&D team for small-molecule APIs
Commercialized Projects
Number of PhD Holders
This data is as of the first half of 2025.
Innovative Drug Programs
Patents Granted
scientific research personnel
Commercialized Projects
Global NDA Filings
scientific research personnel
Pilot-scale production for various specifications
cGMP Kilogram-Scale Laboratory (Taizhou)
· Reactor capacities: multiple systems ranging from 20 to 200 L
· Reaction temperature range: –30°C to 180°C
· Equipped with multiple glove boxes to enable closed material charging
· Designed to support the manufacture of compounds up to OEB 4
MP Kilogram-Scale Laboratory (United States)
· Reactor capacities ranging from 5 to 100 L
· Stainless steel pressure reactors available
· Capable of cGMP-compliant kilogram-scale batch production
cGMP实验室 (台州)
反应釜个数:43个
反应釜规模 :20 - 750L
不锈钢压力反应釜:19L
压力反应釜:0.5 - 2.0L
不锈钢篮式离心机
臭氧发生器
cGMP实验室 (美国)
反应釜规模:72- 750L
不锈钢压力反应釜:19L
压力反应釜:0.5-2.0L
不锈钢篮式离心机
臭氧发生器
公斤级cGMP批次生产
cGMP实验室 (台州)
反应釜个数:43个
反应釜规模 :20 - 750L
不锈钢压力反应釜:19L
压力反应釜:0.5 - 2.0L
不锈钢篮式离心机
臭氧发生器
cGMP实验室 (美国)
反应釜规模:72- 750L
不锈钢压力反应釜:19L
压力反应釜:0.5-2.0L
不锈钢篮式离心机
臭氧发生器
公斤级cGMP批次生产
中试车间 (台州)
生产车间: 8个
反应釜个数:208个
反应釜规模 :30 - 2,000L
反应温度最高:250 ℃
反应温度最低:- 80 ℃
中试车间 (杭州)
生产车间: 8个
反应釜个数:208个
反应釜规模 :30 - 2,000L
反应温度最高:250 ℃
反应温度最低:- 80 ℃
Pilot Plant & Manufacturing Facilities
Manufacturing workshops: 5
Reactor capacities: 500–2,000 L
Maximum reaction temperature: 250°C
Minimum reaction temperature: –80°C
Jiangsu Ruike
· Facilities
6 produiction workshops.
1 solvent recovery workshop.
· Key Equipment
✓306 reactors with a total capacity of 2,228.3 m³
✓ 30 drying units, including three-in-one systems
✓ 30 separation units, including two-in-one systems
✓9 milling units
✓8 distillation columns
✓Reactor sizes ranging from 0.5 to 20 kL, with batch sizes of 200–1,000 kg
Commercial production of APIs for diverse needs
Our multi-site manufacturing network consists of over 50 production lines in large specialized workshops, multipurpose workshops, and pilot plants, offering kilogram- to tonne-scale manufacturing capabilities that accommodate different demands.
Our production facilities are fitted with state-of-the-art, cGMP-qualified API production equipment that facilitate a range of reactions, including high-pressure dehydrogenation and cryogenic reactions. We also built production facilities for highly potent compounds, featuring two OEB 5 and two OEB 4 production lines.
Our production bases utilize automated technologies, including distributed control systems (DCS), to enable automated temperature control and inert gas sample transfer modules. We also implement safety instrumented systems (SIS) for hazardous processes to achieve safe and stable intelligent manufacturing.
Expertise in specialized reactions
High-Pressure Reactions
▪ 14 hydrogenation reactors
▪ Reaction volume: 100 L–10,000 L
Low-Temperature Reactions
▪ 8 cryogenic reactors
▪ Minimum temperature: –90°C
▪ Reaction volume: 200 L–2,000 L
High-Temperature Reactions
▪ Maximum temperature: 350°C
▪ 5 high-pressure reactors
▪ Reactor volume: 1,000 L–2,000 L
Specialized Reactions
▪ Grignard reactions
▪ Enzymatic catalysis
▪ Microchannel reactions
▪ Throughput: 100 kg–100 tons per year
Business Collaboration
Innovative Drug CDMO Services
Tel: 86-576-85588039 / 86-576-85580090
E-mail: bd@jiuzhoupharma.com
